The administration of oxycodone hydrochloride tablets, like all opioid analgesics, may well obscure the analysis or clinical class in individuals with acute abdominal disorders.
If concomitant use is warranted, often evaluate the affected individual, specifically all through treatment initiation and dose adjustment. Discontinue OXYCONTIN if serotonin syndrome is suspected.
Individuals who expertise breakthrough discomfort might require a dosage adjustment of OXYCONTIN or may need rescue medication with an correct dose of a direct-launch analgesic.
There won't be any perfectly-managed clinical reports assessing the protection and efficacy with dosing extra frequently than each twelve hrs. Being a guideline for pediatric individuals eleven a long time and older, the full daily oxycodone dosage usually can be greater by 25% of the present whole day-to-day dosage.
Within the pediatric age team of eleven several years of age and older, systemic publicity of oxycodone is predicted to be similar to adults at any provided dose of OXYCONTIN.
Instruct patients to swallow OXYCONTIN tablets complete; crushing, chewing, or dissolving OXYCONTIN tablets can cause fast release and absorption of the likely lethal dose of oxycodone [see WARNINGS AND Safety measures].
Parenteral drug abuse is usually affiliated with more info transmission of infectious conditions for example hepatitis and HIV.
Respiratory depression can come about Anytime throughout opioid therapy, specially when initiating and next dosage will increase with OXYCONTIN. Think about this hazard when deciding on an Preliminary dose and when making dose adjustments [see WARNINGS AND Safety measures].
Oxycodone, as being the hydrochloride salt, can be a pure agonist opioid whose principal therapeutic action is analgesia and has been in scientific use considering that 1917. Like all pure opioid agonists, there is get more info absolutely no ceiling effect to analgesia, such as is viewed with partial agonists or non-opioid analgesics.
Reserve concomitant prescribing of OXYCONTIN and benzodiazepines or other CNS depressants to be used in people for whom option remedy selections are insufficient.
Accidental ingestion of even a single dose of OXYCONTIN, Specially by little ones, may result in respiratory despair and Demise due to an overdose of oxycodone.
Recommend each clients and caregivers with regard to the pitfalls of more info respiratory despair and sedation when OXYCONTIN is utilised with benzodiazepines or other CNS depressants (together with Liquor and illicit drugs). Advise individuals to not drive or operate large machinery right up until the effects of concomitant use from the benzodiazepine m30xy/m or other CNS depressant have already been established.
In addition, narcotics develop adverse reactions which can obscure the clinical system of people with head injuries.
Shop at space temperature far from light-weight and dampness. Tend click here not to keep in the toilet. Retain all prescription drugs from young children and pets. See also Warning section.